Diethylpropion is a popular weight-loss drug that helps the users to reduce body weight. Read on to known facts and information regarding its composition, dosage, drug interactions and potential side effects.
What is Diethylpropion?
Diethylpropion is a FDA approved appetite suppressant medication similar to Amphetamine. Its mechanism of action involves stimulating the central nervous system to lower your appetite. This prescription drug is used along with a healthy diet and regular exercise to treat obesity. However, the drug is also used for some other purposes such as for treating migraine (off-label use). They are available two different dosages, a 25mg immediate release dose and a 75mg controlled release dose.
The immediate release pills contain 25mg of Diethylpropion hydrochloride (Diethylpropion HLC – a schedule IV controlled substance) while the controlled release tablets have 75mg Diethylpropion hydrochloride.
The inactive ingredients present in the immediate release medicine are mentioned below:
- Diethylpropion Hydrochloride
- Corn Starch
- Magnesium Stearate
- Lactose Monohydrate
- Tartaric Acid
The controlled release form contains the following inactive ingredients:
- Carbomer 934P
- Tartaric acid
- Zinc stearate
The Watson Laboratories, Inc. manufactures these slimming pills. It is sold under the brand name of Tenuate and Tenuate Dospan.
How Does Diethylpropion Work?
These tablets help you to lose weight by suppressing the functioning of the part of the brain responsible for appetite. They also increase the blood pressure and heart rate. As a result, you feel hungry less often and eat less frequently during the day. This leads to gradual weight loss along with an exercise plan and a proper diet.
Seventy-five to hundred percent of the dosage is passed from the body with urine as the drug, along with its metabolites, is excreted chiefly by the kidney.
The Diethylpropion weight loss tablets are designed for short-term usage. The 25mg tablets are usually recommended by doctors. They are taken 3 times a day, one hour before meals. Sometimes, the healthcare provider may suggest you to take one additional evening dose for controlling nighttime hunger. Four 25mg tablets a day is the maximum dose for this weight loss drug.
The long-acting 75mg pills are typically taken once a day, during the mid-morning. They are swallowed whole, instead of chewing or crushing them.
Diethylpropion Missed Dose
In case you forget to take one dose, take the missed dosage immediately as it comes to mind. However, it is advisable to skip the missed dosage if it is already time for the next one. Taking a double dose to make up for the missed one should always be avoided.
It is important to seek immediate medical aid if an overdose is suspected. The common symptoms of overdose include:
- Irregular heartbeat
- Rapid breathing
Diethylpropion Side Effects
It can lead to various side effects which usually go away automatically after a certain period of time. These side effects include:
- Unpleasant taste
- Dry mouth
- Increased urination
- Upset stomach
Long-term use of Diethylpropion can increase the risk of the following serious side effects that require immediate medical attention:
- Blurred vision
- Heart palpitations
- Irregular heartbeat
- Swelling of the ankles or feet
- Skin rash
- Chest pain
- Painful urination
- Difficulty breathing
- Sore throat
Diethylpropion Drug Interactions
It may interact with the following drugs to cause various unpleasant health effects:
- Blood pressure medications
- Oral diabetes medications
- Allergy or cold medicines
- Attention Deficit Hyperactivity Disorder (ADHD) medications like Adderall and Ritalin
- Serotonin reuptake inhibitors (like fluoxetine)
- Bupropion or Diethylpropion
Using the weight loss pill together with the following MAOIs (monoamine oxidase inhibitors) can also cause drug interactions:
- Isocarboxazid (Marplan)
- Tranylcypromine (Parnate)
- Rasagiline (Azilect)
- Phenelzine (Nardil)
- Selegiline (Eldepryl)
- Sertraline (Zoloft)
Some other medications have been checked in combination with it:
- Adipex-P (phentermine)
- Xanax (alprazolam)
- Klonopin (clonazepam)
- Adderall (amphetamine/
This weight loss product should never be used by people who have any of the following conditions:
- Advanced arteriosclerosis
- Idiosyncrasy or hypersensitivity to sympathomimetic amines
- Severe hypertension
- Drug abuse
People using monoamine oxidase inhibitors (MAOIs) should not use it during and within 14 days following the administration of the antidepressant drug. It should also be avoided by people in the habit of drinking too much alcohol as it can cause serious health problems. Special caution is required at the time of general anesthesia in people taking the medication.
Using Diethylpropion during Pregnancy
There is a lack of controlled data regarding its effects during pregnancy. FDA has assigned it to the pregnancy category B. It has been proved that Diethylpropion abuse by a pregnant woman may result in various signs of withdrawal in the neonate. It is not safe for breastfeeding women as the metabolites of this medicine are exerted into the milk and can lead to adverse effects.
You can buy this medication online over the counter. The 75mg Diethylpropion costs about $85 to $95 for thirty tablets while thirty 25mg pills cost between $40 and $45.